If you were to try other combinations/cells/etc. that we have not tested, the pack might be damaged, the bulbs might blow up, the regulation points could be off, the battery low level would certainly don't work as well, etc., etc., etc. - we just don't know. No product is perfect, and I am not claiming that my PhD-M6 is perfect, but based on the 40-50+ packs in use all other the world, the pack seems to work really well with the 3xLiIon cells, and the bulbs/voltages Eric came up with, so that is why I recommend staying within that "envelope"
Will