Running with a headlamp is not my area of expertise, but I'd guess that runners would likely prefer something that offers a good combination of light weight (for comfort) and output. In my mind, other options to consider might include the ZebraLight headlamps that run on single AA batteries like the 200 lumen H51. I'd think the idea of something that would run on readily-available rechargeable AA batteries would be appealing. And in a pinch, a couple of AA alkaline batteries could be easily/cheaply purchased if ever needed at just about any store (not so with CR123A or especially with 18650 batteries).
I also think that dedicated headlamps more or less permanently attached to their headbands take a hit on lack of versatility. For someone who wants it only for running, hey -- that's not necessarily a big deal. But I love the fact that headlamps like those that ZebraLight offers have so much extra (and easy) functionality for other uses in that they can be quickly and easily removed from their headband holders and used for other purposes. Sure, a standard headlamp can be used for other purposes just by turning it on, but it will be clunky in its versatility compared to something like an end-standing ZebraLight (also wearable on a pocket clip and many other ways).
The new ZebraLight H600 might also be a bit heavy for comfort at around triple the weight of one of their AA options -- but I don't run with anything like this, so I don't know for sure how much difference that weight might make to a runner. Maybe it would be just fine.
The options from Spark might be really nice to consider. Certainly by now I'd think there would be other runners who have tried those and provided feedback somewhere...(?)
Increased weight (and "clunkiness") issues might apply to the Fenix headband with multiple lights, depending on the flashlights used. Personally I'd think the Fenix Headband configuration would be uncomfortable and perhaps hard to keep in place for a runner, unless it were really tightened around the head...and then discomfort could really be an issue.
For the original poster, if you haven't seen the comparison of ZebraLight offerings, be sure to look at the comparison chart on their site. Notice also that there are quite a few specifications items not yet filled in on that chart (for instance, for the new SC600).
ZebraLight Comparison Chart