A thousand is ONE REEL for most of the latest-generation LEDs. That isn't considered to be a "large" quantity, really.
THAT SAID, you can sometimes make arrangements to purchase a single reel direct-from-mfr, although most of the manufacturers are partnered up with distributors so that they don't have to deal with order processing for what to them is a drop in the bucket. (For some LEDs a full reel is maybe four hours' production. They ship product out to distributors in cases of reels, often upwards of 20,000 pieces to a case.)
As an aside, my first LED bulk-buy was for 3,400 of Nichia's then-brand-new NPSW500BS LEDs, back in 1997 when the suckers sold for eight bucks per in single qty. Bought them directly from Nichia, who shipped them direct from their then-only plant in Japan. I still have a few brand new LEDs from that batch in an antistatic plastic box for safe keeping, which IIRC was from something like their ninth production run EVER of commercially-available white LED. A little bit of semiconductor-lighting history...
oO