There is a Columbo episode with the villain experiencing a rather serious case of a night of extreme loneliness and contemplation. In the background you hear a lady singing the song "I'm so lonesome I could cry". It's a song most people have heard, but this rendition is a shock and attention getter due to the emotion and purity of delivery. It elicits a search to find the artist since it doesn't seem to appear in the shows credits. Apparently there isn't a cut other than a recording from the Johnny Carson show. Here's the beautiful version by Bernadette Peters.
And then, there is the male version of similar talent. Fabulous!