Series chargers are a bit more temperamental than parellel chargers. Reason being is that not only do they charge 2 cells in order and the risk for reverse-charging is there, if you have an odd number of cells to charge, you're SOL if you can't find a similarly discharged cell to compliment a dual bank. Series chargers gather a charge current similar to 2.8-3.0V per dual-bank and usually charge in pairs at a time. Current is split between the number of banks provided.
Parellel chargers charge cells quicker if they have less cells: for instance, 2 cells will charge quicker than 4 cells in a typical parellel charger. They still run the same risk for reverse-charging, and they are also prone to over/under charge a cell if one cell of an entire chain link is defective. Parallel chargers are either dual banks or, like the CCrane, can charge semi-independantly. Current is divided by how many banks are filled, and as in the case of the CCrane, 4 batteries will split current 4 ways, 2 batteries 2 ways, and the lesser the battery you have, the more current is distributed to a cell...
Independant channel chargers avoid the reverse-charge problem. And if you have a defective cell, you avoid damaging other cells while that one is isolated in an independant circuit. In the case of the Maha C401FS, each channel is provided an independant voltage and current flow...
All three chargers have their pluses and minuses. But I believe independant channel chargers make parellel and series chargers inferior because of its capability to charge in singular, isolate a dead battery, and avoid reverse charging as well as charge odd numbers at the same time.