As any engineer will tell you, the best answer always begins with "It depends..."
Do you want a schematic to build it yourself, or a ready to use, drop in product?
If ready to use, do you want a small lot product (i.e., built in small quantities, typically by a hobbiest - small business) or production product (you can buy 1,000 if you needed to)?
How important are form factor, efficiency, cost? What about features? The quiescent current limit might rule out some microcontroller-based designs, but maybe not - the sleep mode on many families is surprisingly frugal.