Greedy guts?
Every week seems to bring a new theory about why people are getting fatter. The latest is that intestinal microbes are partly to blame
ALTHOUGH most people prefer not to think about it, human guts are full of bacteria. And a good thing, too. These intestinal bugs help digestion, and also stop their disease-causing counterparts from invading. In return, their human hosts provide them with a warm place to live and a share of their meals. It is a symbiotic relationship that has worked well for millions of years.
Now it is working rather too well. A group of researchers led by Jeffrey Gordon, of the Washington University School of Medicine, in St Louis, has found that some types of microbes are a lot better than others at providing usable food to their hosts. In the past, when food was scarce, those who harboured such microbes would have been blessed. These days, paradoxically, they are cursed, for the extra food seems to contribute to obesity. Worse still, these once-benign microbes have even subtler effects, regulating the functioning of human genes and inducing the bodies of their hosts to lay down more fat than would otherwise be the case.
http://www.economist.com/science/displaystory.cfm?story_id=8486096
Every week seems to bring a new theory about why people are getting fatter. The latest is that intestinal microbes are partly to blame
ALTHOUGH most people prefer not to think about it, human guts are full of bacteria. And a good thing, too. These intestinal bugs help digestion, and also stop their disease-causing counterparts from invading. In return, their human hosts provide them with a warm place to live and a share of their meals. It is a symbiotic relationship that has worked well for millions of years.
Now it is working rather too well. A group of researchers led by Jeffrey Gordon, of the Washington University School of Medicine, in St Louis, has found that some types of microbes are a lot better than others at providing usable food to their hosts. In the past, when food was scarce, those who harboured such microbes would have been blessed. These days, paradoxically, they are cursed, for the extra food seems to contribute to obesity. Worse still, these once-benign microbes have even subtler effects, regulating the functioning of human genes and inducing the bodies of their hosts to lay down more fat than would otherwise be the case.
http://www.economist.com/science/displaystory.cfm?story_id=8486096