Funny thread! Two ways that this question could go. Either a current trait will be 'selected against' due to a change in the environment, or a new trait will appear that will be 'selected for' that helps survival in the current or changed environment (that's how it works, you know - Natural Selection.)
If something causes no harm and at the same time gives no advantage (like tailbones, or pubic hair), natural selection doesn't work 'for' or 'against' it. Hence why we still have an appendix and whales and snakes still have hips - doesn't help or hinder.
I'm betting the next "natural selection" event will have to do with our immune system. Something nasty will appear that will do a job on our overpopulated planet, and some folks will have a genetic trait in their immune system that will help them survive. As a result, there will be more survivors with that trait than survivors without that trait. The survivor's genes will be 'selected for'. This means they will produce more offspring in the aftermath (since they outnumber the non-genetic trait population) and most humans will eventually have this genetic trait in their genetic profile.
In a way, HIV is trying to do just that. Some of the survivors of the Bubonic Plague in Europe had a genetic trait in their immune system (Delta 32 mutation of the CCR5 gene) that helped them survive the disease. That trait was passed on to their offspring because those people survived to have children (it was 'selected for'). That trait, as it turns out, has been found by modern scientists (Dr. Stephen O'Brien of the National Institutes of Health in Washington D.C.) to now allow the descendents of those people to survive HIV. Tests have shown that the virus cannot enter their white blood cells at all. Natural selection in action.