You'll have to do a cost and hassle analysis, and weigh that against how tight you are for cash, and how much stuff you have to move.
When my daughter moved from NJ to Florida, she drove her car, and I, our minivan, loaded to the gills, pulling a 4x8 foot trailer open trailer. IIRC, one of the tarps was pretty shreaded by time we got there... it was fortunate for us that it didn't rain on the way down. We were able to unload most of it, and a new neighbor of her's helped me with a couple of items.
When she moved back home, she had accumulated more stuff, and she rented a U-haul, and a trailer for her mid-sized SUV. I flew down. We loaded the truck, again a neighbor helped with a couple of pieces. It was nice having two drivers in one vehicle, and although we stopped for the night there was some piece of mind that the truck (with her stuff) was securely locked.
When I moved from my first house, to my second, it was within the same town, and I made a number of trips with my minivan, the day before the big move. This way I didn't have to pack everything in boxes, and be particularly neat about it. But I hired a professional (but local) moving company to move the furniture and other big stuff, and that which I had boxed up. They moved all of the stuff to the second and third floor. It was worth EVERY PENNY!
When I moved from my second to my third house. I hired the same moving company. They moved all the crap into a huge truck, and when they arrived at the new house. They saw a two car attached garage. The owner offered to save me a hundred, maybe two hundred dollars, (I don't recall) by letting the guys unload the truck into the garage instead of carrying it into the different rooms that it should go into. I laughed out loud... "what do you think? I am out of my mind?"
Three guys on a truck who move stuff for a living can move an incredible amount of stuff in a short period of time. I don't recall, but maybe it took them an hour.
If you plan to do it yourself, who will help you to move the big stuff? Are you capable?
When I moved home from college, I moved a lot of my stuff all the way to the dumpster.