3S4P, absolutely. You will have to be very careful of power dissipation and heatsinking, but as long as the driver is properly attached to a good slug of metal, it should protect itself.
It isn't the relationship of Vout and Iout that you need to worry about, but the relationship of Vin and Vout. As long as Vin > Vout + 0.2V, you will be in regulation (Iout will be what the driver is set to).
If Vin drops too low, then Vout can't be kept up, and thus Vout and Iout will begin to drop. At this point the driver will look like a fixed resistor, around 0.015 ohms (varies a little from one driver to the next). At this point the current is determined primarily by three things: supply voltage, total system resistance, and LED voltage curves.
As far as stacking two systems in a 24V configuration, I don't know exactly what would happen, but my guess is that one would hit the 15V max, and shut down, while the other would get no power to run the LEDs.