For Cree LEDs:
If it's letter-number, it's brightness. If it's number-letter, it's tint. Compare S2 to 5A.
The Cree XP-G S2 aren't necessarily green in tint, but 4sevens got a batch of them, so did Fenix.
If you get more lumens per watt, you get more lumens at a given power level. Most flashlight makers use the same driver with a new LED brightness bin. It costs more money to get a new driver, and would require publishing two runtime specs.
I don't know why they stop at 5.
The Fenix TK21 is not necessarily designed to put out more light. Lumens are emphasized too much anyway. As you buy more lights I think you'll find that control of the light (Output pattern, interface, and tint) are more important than mere output.
Besides, if you want output get an HID light. 3000+ lumens in your pocket.