It depends on the lamp design, but in the case of small ones that have very little electronics in them, like the T10 wedge bulbs, running them on DC will reduce flicker. The T10 wedges rely on the reverse bias voltage of the LED so that it doesn't pop when the polarity inverts in an AC source. As a result, the LED is only on half the time (30Hz in this case), and is the same principle that LED Christmas lights are based on. Some poeple don't notice the flicker at 30Hz, but for some, like me, it can be maddening. Lamps like MR16 or GU10 based lamps that are designed to run on low voltage source will show no real difference when used on AC or DC sources.