What is protein folding and how is folding linked to disease?
Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out these important functions, they assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, in many ways remains a mystery.
Moreover, when proteins do not fold correctly (i.e. "misfold"), there can be serious consequences, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, Huntington's, Parkinson's disease, and many Cancers and cancer-related syndromes.
You can help by simply running a piece of software.
Folding@home is a distributed computing project -- people from throughout the world download and run software to band together to make one of the largest supercomputers in the world. Every computer takes the project closer to our goals. Folding@home uses novel computational methods coupled to distributed computing, to simulate problems millions of times more challenging than previously achieved.
Let's get CPF chugging away on this again. Currently we are 497'th place in contributions, we can do better.
CPF team# 32102 and your CPF screen name.
Basic software download page:
http://folding.stanford.edu/English/Download
Hi performance software page for those with quads and higher liner video cards. ATi 2XXX, 3XXX and 4XXX. Nvidia 8XXX, 9XXX and 200 series video cards.
http://folding.stanford.edu/English/DownloadWinOther
If ya need help the Stanford site and FAQ's cover it well. For additional support there is also the Stanford F@H forums:
http://foldingforum.org/
CPF stats page from Extreme Overclocking site :
http://folding.extremeoverclocking.com/team_summary.php?s=&t=32102
Stanfords CPF stat page:
http://fah-web.stanford.edu/cgi-bin/main.py?teamnum=32102&qtype=teampage
X-CPU's stat page:
http://www.xcpus.com/Folding/FoldingTeamSummary.aspx?teamID=32102&page=1
Click any of the individual members for detailed Folding info.
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