Hello Jason,
To answer your question we need a definition of cycle life.
I believe the industry uses a full charge and discharge to represent one cycle. If you only discharge 20%, you would have to do 5 shallow cycles to get one full cycle.
To get the best cycle life, only discharge 80% of the capacity of the cell, and use a charger that charges to 4.1 volts.
The price you pay for this is reduced capacity.
For example, if you have an 18650 with 2000 mAh capacity, charging it to 4.1 volts will reduce the capacity to around 1800 mAh, and 80% of that leaves you with around 1440 mAh.
In day to day use, this reduced capacity is usually not an issue, and you always have the option to fully charge to 4.2 volts and fully discharge on "special" occasions.
Tom