Photon,
I read a lot of information about Samsung drives before I bought one. The quality of the drives have jumped up in the last several years and they have a 3 year warranty. Seagate has 5 years and tend to be very reliable so I picked the 80GB single platter for reliability and loaded the operating system on it.
My Samsung gets filled up with TV shows, offloaded to DVD-Rs, defragged and filled again. I have not noted any weirdness when doing this and the drive is cool running and the quietest drive I have ever used.
Western Digital and Maxtor have a 1 year warranty so I passed on those. My Samsung drive has a Nidec motor in it which prove to be more reliable and quieter running. Samsung is now bringing out 250GB drives, they only put up to two platters in their drives for much better reliability, cooler running, quietness and low power use.