As I said, I've used both 2x123, 3x123, 1x17670, 2xR123 and 2x17500 cells on my modded G&P. As far as I know, the only thing modded was the emitter to something whiter and a lower Vf. I'm pretty sure it's a TW0H.
If run for 5 minutes or so, in a Vital Gear body, it gets hotter on 2xR123 or 2x14500 cells than it does on 3x123 cells.
I have the DSD charger. After AW pointed out that it's a dumb super dumb charger, I just charge one cell at a time to ensure each cell gets the maximum possible charge out of the DSD. I haven't measured any cells in quite some time but I'm pretty sure I was getting in the 4.0x to 4.1x range. I never saw a 4.2 at all.
I have 6 18650s, 4 17500, 5 14500s, 2 10440s and probably two dozen various R123s. The 17500s see the most charges because they are used in my TL3 which goes through them in 1 hour. I use R123s in many various lights, particularly my HDS EDC light and for that, I use 5 R123s specific to that light and I don't use them in any other lights.
If I were to order a new charger, I'd definately go for the Ultrafire vs the DSD.