Yes. This is because most of Surefire's incand lamps are designed to be used only with their Surefire CR123A primaries, which will voltage sag more than Li-On rechargeables under the same load. A MN10/11 running on 3xCR123As primaries will see about 6-7v under load. However by using 2xLi-Ons, the MN10/11 will be getting 7-8v under load. This decreased voltage sag increases the brightness of the lamp by burning the filament at a higher temperature, not difficult to imagine what happens to a filament when its burning brighter than it was originally designed for right?
The likelihood of the lamp filaments instant-flashing increases in direct proportion to the margins in which the filaments are being overdriven. So if you overdrive a lamp filament by 25%, you'll also being increasing the chances of burning out the filament by 25% and/or decreasing the usable life of the filament by 25% also.
And we haven't even started on the topic of incandescent production tolerances yet, which everyone knows by now varies by a significant margin. For example, take two "identical" P90 lamps and run them on 2xLi-Ons under identical conditions, one lamp can draw 1.5A and the other could draw 1.75A.