The exact definition of 'weapon' is what we always seem to get stuck on. Most of the smaller stuff (man portable) has been used to disrupt optics (both organic and otherwise). The man-portable DAZER was designed to disrupt enemy optical systems, as well as blind people. Needless to say, never quite made it to production, though a couple dozen prototypes were made before the legal and political winds changed.
Getting a little bigger, you have vehicle mounted systems specifically desinged to scan for enemy optics and take them out. The Outrider mounts atop a HMMWV, while the Stingray mounts on a Bradley.
There's an Air Force gadget that mounts in an M203 grenade launcher as a deterrent device. Very bright, but not blinding, lets you know you've been spotted. It's called Saber.
The pulsed impulsive-kill laser, affectionately referred to as PIKL, has had it's ups and downs, but it's a promising technology that would allow tunable effects easier than some more traditional laser technologies.
Course, if you really want power in a small size, you need to go to explosive generators. A one-shot, of course, but gobs of power from a small device.
Trust me, this stuff's all on the web. Certainly the details of some are not for discussion, and the stuff being worked on today... Let's just say, impressive.