If your design isolates the thermal pad from the circuit connections, then you are fine (the thermal pad is electrically neutral, if you only had one LED, you could actually connect the thermal pad to either lead connection and only isolate the 2nd lead connection.
In other words, you could put the entire copper PCB circuit leading to (or from) the LED as one flat "pad" for the entire LED (to aid heat dissipation) except for one of the two corner leads, which would improve thermal dissipation if only a PCB surface is used. Not saying you should do this, but the thermal pad doesn't care if it's part of one side of the circuit or not.
Luxeon and SSC LEDs are different, their pad is NOT electrically neutral, meaning it should be kept separate from ANY part of the circuitry. There is a direct electrical path from the pad to the LED substrate, and so it should always be fully isolated from either end of the circuit.
And what Nake said is also true, if you are only using the top connections, then trimming or filing the bottom connectors resolves any isolation issues.
Hope that helps some