For reference, OS Engines' power rating for this engine assumes fuel with 5% nitromethane content. It can be run with up to 20% nitromethane as long as the fuel has 25% oil.
It's the 25% oil that really makes the difference. It doesn't burn, so it takes heat away from the engine, and such a high oil content keeps the inside of the engine much better-lubricated than RC car engines are. My RC car engines run on 30% nitromethane with only 11% oil, because they would choke if the oil were much higher. That's not a problem with airplane engines, because they run at high RPM the entire time -- they only idle before takeoff and after landing.